Immunologic testing identifies immunologic factors contributing to recurrent pregnancy loss. The immune system of the body detects and attacks things that are different (non-self). Research in this area has led to a greater understanding of pregnancy losses that were previously classified as unexplained. Reproductive immunology is a new field in which few mechanisms to explain the causes of recurrent pregnancy loss are investigated and treated.
Immunologic causes of recurrent pregnancy loss or failure can be treated with immunotherapy. Various forms of immunotherapy have been introduced to treat couples experiencing recurrent pregnancy loss. Understanding the mechanisms involved in recurrent pregnancy loss allows a more focused approach to specific treatment.
Recurrent pregnancy loss is a healthcare concern that needs effective treatment. Before effective treatment can be instituted, a diagnosis must be made. The most common causes of recurrent pregnancy losses are chromosomal abnormalities within the pregnancy itself and immunologic risk factors within the uterus or the environment in which the pregnancy grows. Immunologic causes of occult pregnancy losses are different from early and late pregnancy losses. Once an accurate diagnosis is made and appropriate immunotherapy administered, a live birth rate of 70 to 80 percent can be expected.